How will it affect people being mid-quest?
Aww, Ryme changed the quest while I was keeping records on it.
Oh well. If anyone is interested, I discovered that the Demiurge appeared after I defeated 4 Archons, and that Archons cannot be lasso'd or voodoo'd. That led me to believe that the quest mechanic was similar to how you met Susan: defeat 4 protest instigators to unlock the NC in which you meet Susan.
But now all of that effort is rendered obsolete.
Well, if you checked wiki, you would know that data ranged from 3-6 Archons before Demiurge.